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Use of urine specimens obtained by suprapubic bladder aspiration in order to determine the reliability of culture specimen of urine collected in perineal bag. American Journal of Diseases of Children. It therefore provides an indicator of the overall impact on diagnostic accuracy of the presence of a given covariate.

Table 3 Results bacteriosdopico the regression analysis for dipstick tests for the diagnosis of UTI. In the unweighted analysis, only two items showed a strong evidence of an association with bacterioecopico DOR.

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A number of the items found to be associated with test performance related to specific test methodologies e. Ultrasound for bacterioscopioc detection of reflux, with ultrasound type forced into the model: It is calculated as the odds of positivity among diseased persons, divided by the odds of positivity among non-diseased.

Journal of Clinical Epidemiology. The primary objective exaamen this study was to determine the extent to which variations in the quality of primary studies impact the results of a diagnostic meta-analysis and whether this differs with diagnostic test type.


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Annals of Emergency Medicine. Where sufficient data were available, we used regression analysis to investigate whether individual QUADAS items and additional variables thought likely to be associated with diagnostic accuracy were associated with the DOR and hence whether differences in these items between the studies accounted for some of the observed heterogeneity.

Initially, we performed univariate analysis with all items included separately in the model. All studies included in this review were assessed using QUADAS, an evidence-based tool for the assessment of quality in systematic reviews of diagnostic accuracy studies. Pre-publication history The pre-publication history for this paper can be accessed here: Comparison of ultrasound examination and intravenous urography after a urinary tract infection.

Usefulness of procalcitonin and C-reactive protein rapid tests for the management of children with urinary tract infection. Current imaging of childhood urinary infections: The combination xeamen two screening methods examej a home culture program for children with recurrent bacteriuria. Our assessment of the impact of components of methodological quality on diagnostic accuracy may therefore partially reflect completeness of reporting.

Often factors that lead to an increase in sensitivity will lead to a decrease in specificity and vice versa.

Cost-effectiveness of two methods of screening for asymptomatic bacteriuria. Comparison of ultrasound and dimercaptosuccinic acid scintigraphy changes in acute pyelonephritis.

Interaction terms were not included. A prospective study of imaging modalities in acute pyelonephritis 49 cases: A modified nitrite test as a screening test for significant bacteriuria.


Discussion The methodological quality of primary studies remains a significant issue for systematic reviews of diagnostic tests [ 8, ].

European Journal Of Nuclear Medicine. Use of dipsticks for routine analysis of urine from children with acute abdominal pain. Similarly, although a dxamen of quality checklists for diagnostic accuracy studies have been proposed [ 9 ] and there is growing evidence on the effects of bias in such studies [ 10 ], there has been no rigorously evaluated, evidence-based quality assessment tool for diagnostic studies.

How does study quality affect the results of a diagnostic meta-analysis?

Given the limitations we describe, the results of this study should be treated as hypothesis generating. Ultrasonography in the radiologic evaluation of children with urinary tract infection.

The value of urinalysis in differentiating acute pyelonephritis from lower urinary tract infection in febrile infants. However, where studies are poorly reported the information that can be derived from quality assessment becomes limited.

Annals of Internal Medicine. Tests involving dipstick or microscopy techniques were the only categories where enough studies rxamen available to enable regression analysis. The DOR is used as an overall measure of diagnostic accuracy. Imagerie et premiere infection urinaire de l’enfant: